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Inhibition of ATM with caffeine or the ATM specic inhibitor KU-55933still allowed the formation of RAD51 foci, indicative of an active recombination in theabsence of ATM. It was in his sentinel publication in1948,35 which contained his first 22 cases, that Brunschwig carefully described the en blocremoval of the uterus, cervix, vagina, parametria, the entire internal iliac complex, rectum,bladder, and sometimes, the distal ureters.
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